BLES® (bovine lipid extract surfactant) is intended for intratracheal instillation only after an endotracheal airway has been established. The recommended dosage of BLES® is 5mL/kg at 27mg of phospholipids/mL, which equals 135mg phospholipid/kg. As many as 3 subsequent doses of BLES® can be given within the first 5 days of life.
